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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fb0ce057aa8ae36b253b90c6392050d80fd28f14326870ee56f46fb167fd0b4' 
  AND token = 'X0ydjyhN4Oq1lHpKkc+P8D1VVC0L4rDs1j++WEaA7Tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}