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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '664a6e90e1452649a90d7f56390c9328c65db9dfed966756c555f2bd47c65186' 
  AND token = '9j1D/6vk8ukVVzpXCa+WKw+nnOawN+tr8W68NZCnvjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}