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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb4433b0477d5cca2a2aea9534d20ddb7799483cb91cdd3a2391e93011d01f6a' 
  AND token = 'HQQL2vOM4JhsgUniLTU56SPqtZz1Q+DwZ6RAGU0U280=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}