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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '010d453f1e0dc956b21daa07a909ea195a8c9adfea37556f2fbae950b0faafd7' 
  AND token = 'YHPYyqZtK9psUKI1OOhpV9Q2zOHRyub895WTWHlcMZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}