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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '979dbbe9792c89fccfc974b1e9208885f970c4e7b6132811c632f9a536c4a6a7' 
  AND token = 'eSTD+e4sCgWVRTBgby/wu8dNQnIALqizVPrmVQpbqQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}