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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb49265a6f4244c16064ba13673a3bc1814954b9ecde76095648e17c1625b477' 
  AND token = '4Sx2X3A/6ORS3x+Hd4WJTYYxU3mk8LodbkR5kAKFR/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}