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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c343153c0e078f55af4fd1b39f392f79f87b7cb47b30d17d76b5ead728f885' 
  AND token = 'WhA/Hc4BAEdey89mpR1xRap+9Ateaew49ftvDLejNig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}