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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e5d843b73120d51d609354fd21c3246fcac6069fdafa9163f2492bd26396714' 
  AND token = 'IICMGxmejRkrbAxd/JlFAVJJU9sjGn9bigZu0AL0HLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}