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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '174c9f2142b9378731c3a18f1666f6d2cdc4bd1adaf3a8904204398f50882d23' 
  AND token = 'RCzdQ/LrC06esxWTMqgLLkYZKcD9JW/Tb54c3C1UE7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}