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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '249b146f2f2a77bfe20a7772329bd8eb3e0b973bff30af1dbe7d0cada53ad62c' 
  AND token = 'iswtD6terXy9I7gU6cKF3KI1MxhJo+MBPf56BHPppG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}