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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727b59bf58a7389854345a2563d1449939fea7b30ba57a5115818a2766b1c790' 
  AND token = 'bu9W3798wIDkPAw+B2PYM4ZZE4te06Yz6x/6hLFiRQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}