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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181ab300c1e5ec7c7a32c1a77d20634228a875e4bece80739319f9781273e353' 
  AND token = 'Y1KRjcWxxsGBnj61v7MSsSB6MZk27ypMALA/3icPEGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}