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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57e8d9a7732f93f8d933ce4b991e33d888e091c0df574d6e52d8e44e5cb033d8' 
  AND token = 'WIsUJYfJwBXncP5t1fosJ8HO+jgnqw8BpqMF4AyamQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}