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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8907e9a48ec7b059446b6d40cc9077e8a75dd7b0a650d0f4798bb06d4fc6ddc' 
  AND token = '+hG8L4HCBUHAaV5fHT7lQgooCZePm8DMnpoJridUUbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}