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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8750ac824db5067827a7e5a982c5cd107b899e1abf7d2cd8b5d115573a2c2d3' 
  AND token = 'JrxKwHf8zlUPp51pvl5+ORruhRp4ZlG3OdvXj+5F3MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}