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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73937618842195074d9b37f553060c5830d678976edaa7fd79e12a579350772b' 
  AND token = 'FSDyGkVX5B2B06FDQ8VRH1+xwB7asX/EymRpOj2ZGrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}