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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29eaf1ad0243cd55b4b4b3c90e8780b2743f488bcdbfb26b5363bab4a3ad5447' 
  AND token = 'hhv8HEHl30R4K/MM5E/hxfhhb+wbHBikYUUVSg86Hn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}