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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7758428730b22641c80c659c59fcbbe400a15f849c8d4ee1566b021981be51ab' 
  AND token = '6qPGwHdy4/ONlyMhSmVx8IoP2rkY9xqPeRlbu23BJhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}