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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9b720f4c208a5c8e31902876e6c51db951180ae70df0ec2f75d65f92188503' 
  AND token = '+PtBqe4oB36EOouITTaDVzldEqHyLdLbidl8ATeUkCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}