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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c2f3bb0a62ed1c010a5cde0097cb6b56b2038fda81393feeb2b42955a758cec' 
  AND token = 'gDDkZusej3XibAmgUjDXtyumos+Sc3Tz0a2FpmCNEfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}