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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8a5bb27b970f3c4de999aaff93146707feefb648ce68499285de0e88d5904aa' 
  AND token = '5F+1OPa2ilz4Es1x1YVYqupvPhVhh1Mt291UdXuTZnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}