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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12f3901aa3d79d8bed25dbcd5fd11a0f67d88667e4c7035114dfd12b10b2d206' 
  AND token = '4jNjvdYB4o2dokznTyVJjfF9TySdeWXxXTG5aP34hoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}