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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b857a24dde7ef8f5880df0fd6a21b7af7439035c76219774f4429d3843a513fe' 
  AND token = '08LeG2ESBudVEPoysInsu7k94+VW8t0VqbVLaca9sR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}