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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4877ee50e195815df5eb22f3aab69a291715b492273229bb137762f8acebe613' 
  AND token = '20EbDil8v1v3SFDaWPFjaQer326H+MMy9X06WWko5Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}