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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4f37c1171f4b1ddeda6a9dee5fdb5d01f5350fa9756651fd213e15fd23e4376' 
  AND token = 'B+bt2xbg+JUgoHJCF/TnPvcbG7BznAZQIUwLdrkHtsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}