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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0027ca5d14511a4e814ba11cd84237f7451f43b4a881cc72573c529cd223bb' 
  AND token = '7a/iO+6XbZWvVkrf+2RiqhBDFhhYizXDba8aTl8Nggg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}