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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377ca9418f13d3d2bbc2a1fd1c700f3b2a0a12081e71d07209166623f7c0c3cb' 
  AND token = 'BkIFhKaPduvUJX9jNBQ9cZTVZw7v8FwJJcaXX+NmZ3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}