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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589868c7cac0c4cd8d2db6e052eb34a09caad644977f282d3c7e2f5a7af38352' 
  AND token = 'JoFcX6b0GNOXdayrwCN+fk0g0Hf/CSc13dGlDUyeEpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}