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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff642a848d2767388ed21ce11f1f72b18f6a84e386f5e3781ea2c930a8903794' 
  AND token = '0/lM1Alr44Dp8jsdmmtvbVfw2wgj91suzyRJ1X/OKm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}