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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256004ae8ff31bd74781a018caa53c2eb07dcebb41402ea2e443c2abd88be940' 
  AND token = 'wcxZE1FP14tRoKfaAYR1Sm+Ne6ibzqLidzcMDOMhVP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}