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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e9fd89d3d7fa06ded2763d38b7b8a41aa73072fbaf316d72ae9a789c76b79c0' 
  AND token = 'kkZ/5U2LY/Gda5+2Oe6Q08hSzqWsCs1DxyHfao3XMbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}