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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '779330734a0a007dc6e95013df014d26eea5a31ae7eac7f4162efd03222a58a8' 
  AND token = 'R1IDJ0sWGk0lep7pj+00BFiMFJRURbiDSYleGPyiuGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}