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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54e5e57e56d7df3ef1c0bbd35f521e885831a57e0f956e52d6874a19f33f125d' 
  AND token = 'YJr/BDGYBuYaNnFvOOTYdRFDGHvSTrzdMCbwjFtHp6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}