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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b791a0a655097a556d9ec2ca14cf01541006c6a1795d2f4c6f1ee4c6a230ad' 
  AND token = 'hFWAxSlUu10fSwZUrQzBepwpZG8agWB5NPbKEuy0S1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}