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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b47949c5fba5483fc1cbb9e4b56e62e838c9b5f4f4c4b242630e52ace05fa2d' 
  AND token = 'dAfoTbNYbbOGw6wiZ8S1csKfxzo+SwF4ekCrGhcdKSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}