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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e11ce151c973d81154ceaa0efdf13dd595d35766ad33ddaad6a2d9a2fdbe10c' 
  AND token = '6+Vh7B/HZ2LKF6lTZDwOfHEWEFtPhUoZs4ry3J833e0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}