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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aa450e4c2f37283f9213a863d54fb656274361ddef5389e051f5dd86c6efa04' 
  AND token = 'XUumHYgVH+FbUPFoFEf0bvaFe6409zXR/i7yah0STjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}