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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b746257e31acc102b5aa3aa6b1e1ec9bea2b68939fc1398a841fbe318dab860' 
  AND token = 'Dsdml++kbZAOWJikK/Lbamd740+FXjHnvXp1caVHDH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}