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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c60450cfb4e348d1e2b164b41986e66fb5e6dec06062a039859678d9d489a12' 
  AND token = 'DShnr3rxz2doSdzqbTpK8vR/vE4oEu5+/9+o7aalTwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}