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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd420c201243ceaeab77d2d7404186075a9dd01d7e1bb6658908f83743e60b121' 
  AND token = 'W0BN6qL0cUfSYEduzwQnjHukIWR0h8fc6fXZYTYxLhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}