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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '373285ec525dc2784b7af9afeba08717fa1a699aff927277d575210b600f0ac3' 
  AND token = 'DFi6RsCQ5xT1HzHLuDo/Hx1LvqJPKW0TkUnLu+Q4fQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}