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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '012de24dcd3b24210d5c46e43df15792f711799d701416676a32b93380dd7a49' 
  AND token = 'yx2aS6zClmOlhkMz5wufTSK9H3d1FawPHxYsAoOqdNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}