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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '579e7c43e8d63c0c49649484c38e4e2b86b8bac3335a055c3e220b019d4820a1' 
  AND token = 'u/Z2h2Kw2IKBQ0pBQaLuCZD9M6chcHPMFIV2iHCyi2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}