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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8b626adc3324e69e0c8fb56a5422260a04c5023cb24594581ea18aa108c10b8' 
  AND token = 'la3DgIUmwTUMErPX1SX8zGdRaDfDiJ/1bZICyg5v2wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}