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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a7d454e7496999041861f0ac4998c40aa5aa38ce65644eef171e681891e9ea0' 
  AND token = 'CZ+Fz8TNlVX4O/nQ3mIVueFx0tFxcG4p4gltkTdEr1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}