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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e15be8b78fa1644f90c0b26c4915508daa12de1ba95490fa7e41c09f4ffbdf40' 
  AND token = 'IyS3hXAoHIz7QCQU+Y1yiiDfKyMwdcTGziYDuJTJAIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}