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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757ed4b788543f02d840a4eeab588d868a027ae03783752b8d25b80c49ff4937' 
  AND token = 'PByiPwVIai0FFFdyd9KCAAqT1PRYeAxdJ01Q472yxQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}