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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ac7abe4d694378b27695ddf6d870c0e8aa2725f237f18a78f4aef303e74b089' 
  AND token = '2jpwxt6xB8bFrXJtuswAOXXjjiv+PJvsuKbYyfmweac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}