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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d7a5f7dd20c03276d76fd0ea144fdda8be8ce2d4683ad03c31d8686534f39ae' 
  AND token = 'H8sFOgt5EMOIVA+s2V2k2MmpID+wrn0J2N5JHUlicDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}