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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764b044ab753de6b9e8643704d6b4288ea14999735deaa60f9124060c92f7159' 
  AND token = 'ifbBYG5ECzWL6XP4W298RAHzhFcSqqRqs2Q0CEj/Pms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}